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Monday, August 04, 2014

Oprah Winfrey once said, “I feel that luck is preparation meeting opportunity.”  It turns out that most of the scientific discoveries were strokes of serendipity made by scientists on an alternative quest. And we can take comfort in the fact that genius arrives not by choice but by chance to these inventors who have changed the world in one way or the other. Here are the three inventions that owe as much to luck as judgment and the science behind them!
The big bang 
It has been 50 years since the ground breaking discovery about how our universe was formed is known. But surprisingly it was not an ‘aha’ moment for the Nobel Prize winners Amo Penzias and Robert Wilson. Instead it was a story of frustration! They both were frustrated that their telescope which they used to observe the space was not functioning properly. It was giving this background noise which made them think if a pigeon was trapped inside it; it was polluting the data they were really after.
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But, later they realized that this noise was actually traces of some of the earliest light also known as the cosmic microwave background radiation. How did the duo find this left over light from 13.7 billion years ago?
The science is that when the universe cooled enough from the initial hot and dense state, it allowed photons to flow freely throughout the cosmos. This light has been travelling since then and showed up as up as static on Bell Labs’ six-meter Horn Antenna radio telescope. The persisting light formed radio and micro waves that matched the predictions of the 1920 big bang theory.
Thus, this discovery was the first evidence that the universe started off compact and is expanding ever since! 
Stainless Steel
What can a wrong mixture of elements can do to humanity is called Stainless Steel. As the name suggests this form of steel is more resistant to corrosion than any other alloy steel with varying carbon percentage.
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Although, steel was invented way before stainless steel, it was by accident that Harry Brearley a chemist discovered this most important metal in 1913. Harry was given a responsibility to develop a steel alloy that could withstand extreme heat inside a rifle barrel, while doing so, he started making different combinations of alloys using different combinations chromium and carbon. Accidently his eyes rolled onto a still shiny and bright metal piece that had sustained corrosion and dug up the formula for ‘rustless steel’ or stainless steel as we know it to be 12% chromium.
How did 12% chromium protect the steel from rusting?
When exposed to friction heat in the rifle barrel, this steel formed a sheet of oxygen around it and protected it from rusting. High chromium content steel sustained the routine acid test making Harry realize the potential of his discovery! 
The stainless steel that we use today has high amount of chromium and carbon. They both oxidize at the decarburization of melt at temperature greater than 122 degree Celsius when both the elements are in pure state. Thus, stainless steel is formed at all temperatures above 1800 degree Celsius when carbon oxidation occurs. 
Chromite, FeCr2O4, is extensively used for extraction of chromium in a stainless steel ore. A low carbon ferrochrome formed by the reduction of chromite with coke in an arc furnace is used to produce steel that is stainless and hard! 
Penicillin
No accident story is complete without Penicillin, and it is for Sir Alexander Fleming that we could survive small infections since 1929! This story is retold a million times, Sir Fleming went a vacation in midst of a never ending search for a magical drug that cures all diseases and came back to discover a mould growing on his petri dishes. When he left, the dishes were covered in colonies of bacteria, except around the area where the mold was growing.  And this area was free of bacteria like the mold had blocked the bacteria from growing any further. But do you know the science behind it? Let’s strain! 
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Since Fleming was working with a particular strain of bacteria called as Staphylococcus, one petri dish which was accidentally left open had a mold growing on it, but what was unusual was that there was no bacterium around the mold. He took the ingredients of the mould and grew a pure fresh culture which was identified as Penicillium notatu
Later, while describing the filtrate and the broth culture he coined the term ‘Penicillin’ and grew it with gram positive as well as gram negative bacteria and fungi. The bacterium was lysed and penicillin was started to be used as a disinfectant since it was highly potent, has minimum toxicity and also plays a vital role in isolating Bacillus influenza.
A decade later, Howard Florey and Ernst Chain dug deep into Fleming’s research and isolated powdered penicillin from the mould in a process that involves freeze drying Penicillin and then subjecting it to ice evaporation under vacuum.  All the three researchers won the Nobel Prize in medicine in 1945. 
Besides being discovered by accident, there is one more thing common in these discoveries and it is keen observation.  All the scientists who are victims to these happy accidents had an eye for detail and keenly looked into the failed experiments and made progress.  We fondly call all the progress by accident, serendipity.